Zofran and Sleepiness: What's the Connection?
Zofran (ondansetron) is widely used to treat nausea and vomiting. It is important to be aware that it can also cause sleepiness. This medication can lead to drowsiness, fatigue, and a feeling of being unfocused.
Why Does Zofran Make You Sleepy?
Zofran blocks the action of serotonin, a neurotransmitter that influences many bodily functions, including nausea and sleep. This alteration in serotonin levels can contribute to feelings of sleepiness.
How Sleepy Will I Be?
The level of sleepiness from Zofran can vary among individuals. Some may experience only mild drowsiness, while others may feel significantly more tired. The dosage of Zofran can also affect how sleepy you feel; higher doses are often linked to increased drowsiness.
What Can I Do About the Sleepiness?
If Zofran makes you excessively sleepy, consider these options:
- Consult your doctor about possibly reducing your dose.
- Take Zofran in the evening to sleep through the drowsiness.
- Refrain from driving or operating heavy machinery while on Zofran.
- Stay well-hydrated to help eliminate the medication from your system.
When to Worry
In most cases, drowsiness caused by Zofran is not a significant concern. If you encounter severe fatigue or difficulty staying awake, contact your doctor promptly.
The Bottom Line
Zofran is an effective medication for treating nausea and vomiting, but it may also cause sleepiness. If sleepiness becomes an issue, discuss management strategies with your doctor.
